Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics

摘要

The invention provides an electronic controlled method for combinatorial synthesis of a biopolymer at micro-locations. Such a method allows self-directed synthesis to occur without the need for any outside direction or influence. The combinatorial synthesis involves the transportation, concentration and reaction of monomers, coupling reagents, or deblocking reagents at addressable micro-locations.