METHOD AND DEVICE FOR APPLICATIONS OF SELECTIVE ORGAN COOLING

摘要

The invention provides a method and device for heating or cooling a surrounding fluid in a feeding vessel. The device includes a catheter assembly capable of insertion to a selected feeding vessel in the vascular system of a patient. The assembly includes a heat transfer element at a distal end of the catheter assembly, the heat transfer element (14) having a plurality of exterior surface irregularities (20, 24) shaped and arranged to create turbulence in a surrounding fluid, the surface irregularities (20, 24) having a depth at least equal to the boundary layer thickness of flow of the surrounding fluid in the feeding vessel. The assembly also includes a supply catheter (12) to deliver a working fluid to an interior of the heat transfer element (14), a return catheter (202) to return a working fluid from the interior of the heat transfer element (14), and a drug delivery catheter (312) running substantially parallel to the axis of the catheter assembly.