METHOD FOR THE MODULATION OF FUNCTION OF TRANSCRIPTION FACTORS
摘要
There is provided a method of modulating the function of transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding sites for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of transcription factors and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors play a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor.
申请公布号
WO0006696(A2)
申请公布日期
2000.02.10
申请号
WO1999US17366
申请日期
1999.07.30
申请人
UNIVERSITY OF SOUTH FLORIDA;ZUCKERMAN, KENNETH, S.;LIU, RICHARD, Y.