发明名称 METHOD FOR THE MODULATION OF FUNCTION OF TRANSCRIPTION FACTORS
摘要 There is provided a method of modulating the function of transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding sites for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of transcription factors and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors play a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor.
申请公布号 WO0006696(A2) 申请公布日期 2000.02.10
申请号 WO1999US17366 申请日期 1999.07.30
申请人 UNIVERSITY OF SOUTH FLORIDA;ZUCKERMAN, KENNETH, S.;LIU, RICHARD, Y. 发明人 ZUCKERMAN, KENNETH, S.;LIU, RICHARD, Y.
分类号 A61K38/00;A61K48/00;C12N15/113;(IPC1-7):C12N/ 主分类号 A61K38/00
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