发明名称 PROCESS FOR THE PREPARATION OF ACYL DERIVATIVES
摘要 For the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 1. A process for the manufacture of acyl derivatives of general formula I see diagramm : EP0030294,P12,F1 in which R represents hydrogen or a readily hydrolyzable ester group, as well as of salts of these compounds and hydrates of these compounds or of their salts by reating a halide of general formula II see diagramm : EP0030294,P12,F2 in which R has the significance given above and Y represents a halogen atom, or a salt of this compound with thiourea and, if desired, converting a compound of formula I obtained into a salt or hydrate or into a hydrate of this salt, characterized in that X signifies one of the groups see diagramm : EP0030294,P13,F3 in which R' represents hydrogen or a readily hydrolysable ether group.
申请公布号 PT72084(A) 申请公布日期 1980.12.01
申请号 PT19800072084 申请日期 1980.11.20
申请人 F. HOFFMANN-LA ROCHE & CIE. SOCIETE ANONYME 发明人
分类号 C07D501/00;A61K31/545;A61K31/546;A61P31/04;C07C;C07D;C07D501/04;C07D501/16;C07D501/36;C07D501/46 主分类号 C07D501/00
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