| 摘要 |
<p>Novel DELTA 4-androstenes of the formula <IMAGE> I wherein R1 is alkyl of 1 to 3 carbon atoms, Y is selected from the group consisting of hydrogen, fluorine and methyl, R2 is selected from the group consisting of saturated and unsaturated alkyl of 1 to 12 carbon atoms, -CF3, aryl of 6 to 12 carbon atoms and aralkyl of 7 to 12 carbon atoms and the dotted lines in the A and B rings indicate the optional presence of one or two double bonds in the 1(2) and 6(7)-positions with the proviso that when R1 is methyl, R2 is saturated or unsaturated alkyl and the B ring is saturated, Y is methyl having anti-inflammatory activity and novel intermediates.</p> |
