发明名称 |
Process for therapeutic treatment |
摘要 |
This invention relates to a new method of therapy comprising the administration of a pro-drug to a human or animal, said pro-drug being a compound formed by a therapeutic compound chemically combined with another moiety by a photocleavable bond and irradiating the diseased area with ultraviolet radiation in an amount sufficient to cleave the bond and release the therapeutic compound in a therapeutically effective amount. Specifically disclosed are pro-drugs which are cleaved to therapeutically active medications which are anti-proliferative and anti-inflammatory compounds and the treatment of inflammatory and/or proliferative skin diseases therewith.
|
申请公布号 |
US4235887(A) |
申请公布日期 |
1980.11.25 |
申请号 |
US19770787230 |
申请日期 |
1977.04.13 |
申请人 |
UPJOHN CO THE;REGENTS OF THE UNIV OF MICHIGAN |
发明人 |
VOORHEES, JOHN J;WIERENGA, WENDELL |
分类号 |
A61K31/135;A61K31/00;A61K31/15;A61K31/155;A61K31/165;A61K31/17;A61K31/18;A61K31/195;A61K31/215;A61K31/22;A61K31/57;A61K31/573;A61K45/08;A61P17/00;C07C205/42;C07D239/54;C07J41/00;(IPC1-7):A61K31/705 |
主分类号 |
A61K31/135 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|