发明名称 Pyrazolyl amino imidazolines as antihypertensive agents
摘要 Described is a method of treating hypertensive by administering to mammalian patients compounds of the formula <IMAGE> wherein R1 and R2 are hydrogen, loweralkyl, lowercycloalkyl, aralkyl, aryl, pyridyl, isoquinolyl, phthalazinyl, or aryl substituted by one or more hydrogen, halo, loweralkyl, lowercycloalkyl, haloloweralkyl, haloloweralkyl, aminosulfonyl, nitro, hydroxy, alkoxy, carboxy, alkoxycarbonyl, cycloalkoxy carbonyl, aminocarbonyl, diloweralkylaminocarbonyl or <IMAGE> wherein n is 4 or 5. R3 is hydrogen, halogen, loweralkyl or aryl, and R4 is hydrogen, acyl, amino or loweralkyl, and the pharmaceutically acceptable acid addition salts thereof.
申请公布号 US4234594(A) 申请公布日期 1980.11.18
申请号 US19790036884 申请日期 1979.05.07
申请人 ABBOTT LABORATORIES 发明人 WINN, MARTIN;NORDEEN, CARL W.;ARENDSEN, DAVID L.
分类号 C07D231/38;C07D231/40;(IPC1-7):A61K31/40;A61K31/47;A61K31/41;A61K31/43 主分类号 C07D231/38
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