| 摘要 |
A racemic mixture of N-acetyl-D,L-phenylalanine methyl ester is provided and subjected to the action in an aqueous system of microbially derived serine proteinase. The N-acetyl-L-phenylalanine methyl ester is selectively converted to N-acetyl-L-phenylalanine, which is separated from the unreacted N-acetyl-D-phenylalanine methyl ester, which is then separately recovered. Recycle of either a D or an L component, with racemization to provide a D,L mixture, affords methods of completely converting an original racemic mixture to either optically active isomer form as needed. |
