| 发明名称 |
HSP90 INHIBITORS, METHODS OF MAKING AND USES THEREFOR |
| 摘要 |
<p>The invention provides purified 18,21-didehydro-18,21-dideoxo-18,21-dihydroxy-geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents that are useful for the treatment and/or the amelioration of symptoms of cancer and other proliferative tissue disorders.</p> |
| 申请公布号 |
EP1863769(A2) |
申请公布日期 |
2007.12.12 |
| 申请号 |
EP20050810418 |
申请日期 |
2005.08.31 |
| 申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
ROSS, DAVID;SIEGEL, DAVID;GUSTAFSON, DANIEL, L.;GUO, WENCHANG;REIGAN, PHILIP |
| 分类号 |
C07D225/04;A61K31/33;A61K31/395;A61K31/40;C07D225/06 |
主分类号 |
C07D225/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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