Novel soluble derivatives of 2,4-diamino pyrimidine

摘要

The novel derivatives correspond to the general formula II: <IMAGE> (II) in which: R1 R2 R3 and R4 represent identical or different groups which can each be a hydrogen or halogen atom or an alkyl group, alkoxy, or benzyloxy group and R is the residue of an R-CHO aldehyde selected from among linear or branched saturated aliphatic aldehydes including 1 to 4 carbon atoms or again represents the Z-CH=CH radical in which Z represents a hydrogen atom, a linear or branched saturated alkyl group, an aromatic nucleus or an aromatic heterocyclic nucleus or again R represents the radical HO CH2 (CH OH)n-in which n has the value of 3 or 4. The novel compounds have high solubility in water and antibacterial activity and potentiating power.