发明名称 Process for the preparation of phenylalkylamines
摘要 The compounds of formula I in which the symbols have the meaning given in Claim 1 are prepared by reaction of a corresponding compound having, in place of the group -NB, a tosyloxy radical with an amine of formula H-N=B. The ketones obtained (formula I) can be converted to secondary alcohols or oximes and reduced to the &rdurule& CH2 stage and each time to acid addition salts. They are useful as medicaments, in particular as antiinflammatory agents. <IMAGE>
申请公布号 CH619923(A5) 申请公布日期 1980.10.31
申请号 CH19790005488 申请日期 1979.06.12
申请人 STERLING DRUG INC. 发明人 BERNARD LEON ZENITZ
分类号 A61K31/135;C07C67/00;C07C209/00;C07C209/16;C07C209/28;C07C209/40;C07C209/50;C07C213/00;C07C215/32;C07C215/52;C07C217/60;C07C225/16;C07C239/00;C07C251/48;C07C313/00;C07C315/04;C07C317/32;C07C323/36;C07C323/47;C07D207/06;C07D207/20;C07D211/12;C07D211/14;C07D211/16;C07D213/16;C07D285/08;C07D295/096;C07D295/112;C07D295/135;C07D309/12;C07D491/10;C07D491/113;(IPC1-7):C07C97/10;C07C91/16;C07C131/00 主分类号 A61K31/135
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