摘要 |
Compound, with hypoglycaemic activity, having formula (II) or a pharmaceutically acceptable quaternary ammonium or acid addition salt thereof: <CHEM> wherein R<1> and R<2> are substituents attached to any of the carbon atoms of the dihydropyridine ring and represent hydrogen, C1-6 alkyl, halogen, carbo-C1-6 alkoxy or R<3> represents hydrogen, C1-6 alkyl, phenyl or benzyl; R<4> represents hydrogen or C1-6 alkyl; R<5> represents C1-6 alkyl, phenyl optionally substituted with up to 3 groups selected from halogen, C1-6 alkyl, and C1-6 alkoxy; or benzyl optionally substituted with up to 3 groups selected from halogen, C1-6 alkyl and C1-6 alkoxy; or R<4> and R<5> together represent the remaining members of a 5- or 6- |