发明名称 SALICYLAMIDE ESTERS HAVING THEREPEUTICAL ACITIVITY, PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
摘要 Esters of salicylamide with anti-inflammatory and analgesic action are disclosed. These esters have the following general formula: <IMAGE> (I) wherein R is a radical of an acid selected among d-2-(6'-methoxy-2'-naphtyl)-propionic acid, 2[[3-(trifluoromethyl)phenyl]-amino]-3-pyridine carboxylic acid, 2- {[3-(trifluoromethyl)-phenyl]-amino}-3-pyridincarboxylic acid, 2-(4-isobutyl-phenyl)-propionic acid, 4-allyloxy-3-chloro-phenylacetic acid, 2-(3-benzoylphenyl)-propionic acid, 2-[(2,3-dimethylphenyl)amino]-benzoic acid and 2[[3-trifluoromethyl)phenyl]-amino]benzoic acid. The process for preparing the subject esters comprises reacting a halide, preferably a chloride of the desired acid, with a solution of salicylamide.
申请公布号 ZA8001598(B) 申请公布日期 1980.10.29
申请号 ZA19800001598 申请日期 1980.03.19
申请人 NEOPHARMED S P A 发明人 REINER A
分类号 A61K31/60;A61K31/215;A61P25/04;A61P29/00;C07C67/00;C07C231/00;C07C231/12;C07C235/46;C07D213/80 主分类号 A61K31/60
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