Immobilized microbial enzyme/cell systems, process for their production and their use in preparing alpha-keto acids from the corresponding amino acids.

摘要

According to the invention, alpha -keto acids are prepared from the corresponding amino acids by using a biocatalyst of a microbial origin, which has been immobilized in a polymeric matrix. The immobilized biocatalyst is effective and specific for the synthesis of alpha -keto acids from D-amino acids. The product can easily be separated from the particulate catalyst. In the synthesis reaction, hydrogen, peroxide is formed, which is decomposed by a catalyst which also is immobilized in the polymeric matrix. The invention can be used in continuous or discontinuous processes for the preparation of alpha -keto acids from the corresponding D,L- or D-amino acids.