| 摘要 |
<p>The 1- and d1-(racomic) forms of the compounds of the formula: ...(I), wherein R is H or CH3, and the non-toxic acid addition salts thereof, useful as antihelmintic compounds are disclosed. The compounds may be prepared by reacting 1- or d16-(m-aminophenyl)-2,3,5,6-tetrahydroimidazo¢2,1-b!thiazole with an acid of the formula: ...(III), wherein R is H or CH3, or with its functional equivalent as an acylating agent, and if desired, when the d1- form of the thiazole starting material is used, resolving the d1- product so as to obtain the 1- form, and if desired, converting an 1- or d1- form of a compound of the Formula (I), into a non-toxic addition salt by reaction with a suitable acid.</p> |
