| 摘要 |
<p>PREPARATION OF N,N'-DICARBOXYMETHYL-1,3-PROPANEDIAMINES N,N'-Dicarboxymethyl-1,3-propanediamine (designated PDDA) is prepared by reacting 1,3-propanediamine with formaldehyde and HCN to form hexahydroprimidine-1,3-diacetonitrile, which is hydrolyzed with an aqueous alkali metal hydroxide to form dialkali metal hexahydropyrimidine1,3-diacetate which, in turn, is reacted with mineral acid to form the desired PDDA and formaldehyde. N,N'-Dicarboxymethyl-2-hydroxy-1,3-propanediamine(designated HYDROXY-PDDA) is prepared by reacting 1,3-diamino-2-propanol with formaldehyde and HCN to form 5-hydroxyhexa-hydropyrimidine-1,3-diacetonitrile, which is hydrolyzed with an aqueous alkali metal hydroxide to form dialkali in turn, is reacted with acid to form the desired HYDROXYPDDA and formaldehyde.</p> |
