发明名称 IBUPROFEN P-HYDROXYPHENYLUREA ESTER
摘要 <p>Ibuprofen p-hydroxyphenylurea ester having the formula 11: was prepared from the free acid, ibuprofen ¢+2-(p-isobutyl-phenyl)propionic acid! (1). The ester 11 above has the anti-inflammatory activity of the free acid, but in contradistinction to it, it has a pleasant taste, suitable for oral administration such as uncoated tablets, suspensions or syrups, for the treatment of inflammatory conditions, particularly arthritis.</p>
申请公布号 CA1088094(A) 申请公布日期 1980.10.21
申请号 CA19770278818 申请日期 1977.05.19
申请人 UPJPHN COMPANY (THE) 发明人 SINKULA, ANTHONY A.
分类号 A61K31/215;A61K31/265;A61P29/00;C07C67/00;C07C239/00;C07C275/34;(IPC1-7):07C127/19 主分类号 A61K31/215
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