发明名称 |
NOVEL INDOLE COMPOUND*DRUG THEREFROM AND ITS MANUFACTURE |
摘要 |
Novel 3-(1-Imidazolylalkyl)indoles and the pharmaceutically acceptable acid addition salts thereof are disclosed. The novel compounds are useful in selectively inhibiting the action of the thromboxane synthetase enzyme without significantly inhibiting the action of the prostacycline synthetase or cyclooxygenase enzymes and are thus of value as therapeutic agents for the treatment of ischaemic heart disease, stroke, transient ischaemic attack, thrombosis, migraine and the vascular complications of diabetes. |
申请公布号 |
JPS55133380(A) |
申请公布日期 |
1980.10.17 |
申请号 |
JP19800028563 |
申请日期 |
1980.03.06 |
申请人 |
PFIZER |
发明人 |
PIITAA EDOWAADO KUROSU;ROJIYAA PIITAA DEITSUKINSON |
分类号 |
C07D409/14;A61K31/415;A61K31/4178;A61K31/425;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/505;A61P7/02;A61P7/06;A61P9/00;A61P9/08;A61P9/10;A61P25/04;A61P25/06;A61P43/00;C07D209/08;C07D233/06;C07D333/00;C07D401/14;C07D403/06;C07D403/14;C07D405/14;C07D417/14;C07D521/00;(IPC1-7):C07D403/06 |
主分类号 |
C07D409/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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