| 发明名称 |
COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a compound for facilitating drug delivery to a target cell.SOLUTION: The present invention provides a compound represented by the formula: (targeting molecule) n-linker-(targeting molecule)n (where, the targeting molecule is a retinoid or a fat soluble vitamin having a specific receptor on the target cell; n is an integer of 0-3; the linker is a polyethylene glycol (PEG) or PEG-like molecule).SELECTED DRAWING: None |
| 申请公布号 |
JP2016153477(A) |
申请公布日期 |
2016.08.25 |
| 申请号 |
JP20160006249 |
申请日期 |
2016.01.15 |
| 申请人 |
NITTO DENKO CORP |
发明人 |
NIITSU YOSHIRO;JOSEPH E PAYNE;HOU ZHENG;JOHN A GAUDETTE;LOREN A PERELMAN;TANAKA YASUYUKI;VIOLETTA AKOPIAN;PRIYA KARMALI;SRIDHAR C NAGARAJAN;VISTOR KNOPOV;RICHARD P WITTE;MOHAMMAD AHMADIAN |
| 分类号 |
C08G65/335;A61K47/18;A61K47/20;A61K47/24;A61K47/28;A61K47/34;C08G65/333 |
主分类号 |
C08G65/335 |
| 代理机构 |
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