发明名称 |
Dobbeltvirkende farmaceutiske sammensætninger baserede på superstrukturer af angiotensinreceptor antagonister/blokkere (arb) og neutral endopeptidase (nep) inhibitorer |
摘要 |
Solid oral dosage forms, especially tablets, of a pharmaceutical composition comprising a supramolecular complex can be formed from a direct compression process or a compaction process such as roller compaction. Such solid oral dosage forms feature an immediate release profile that allows for fast release of the therapeutic agent. A particularly useful supramolecular complex is trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate-(S)-3'-methyl-2'-(pentanoyl{2"-(tetrazol-5-ylate)biphenyl-4'-ylmethyl}amino)butyrate]hemipentahydrate. |
申请公布号 |
DK2295035(T3) |
申请公布日期 |
2016.08.29 |
申请号 |
DK20100173506T |
申请日期 |
2008.11.04 |
申请人 |
Novartis AG |
发明人 |
Al-Fayoumi, Suliman;Hu, Jiahui;Kumaraperumal, Natrajan;ROYCE, Alan Edward;RUEGGER, Colleen;Zannou, Erika Aina |
分类号 |
A61K9/00;A61K9/20;A61K31/216;A61K31/41 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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