Novel heterocyclic anthracycline compounds, processes for their preparation and pharmaceutical compositions containing them.

摘要

There are disclosed novel heterocyclic anthracycline compounds having antitumor activity against murine P388 leukemia in mice, processes for preparing the novel compounds and pharmaceutical compositions containing them. The novel compounds have the formula:
<CHEM>
wherein R is hydrogen or hydroxy and X, Y or Z may be sulfur with the proviso that when X is sulfur then Y and Z are both CH and when Y is sulfur then X and Z are both CH and when Z is sulfur then X and Y are both CH, or the formula:
<CHEM>