SUBSTITUTED 1-PIPERAZINYL-TRIAZOLO-THIENO-1,4- DIAZEPINES

摘要

This invention relates to novel substituted 1-piperazino-4H-s-triazolo3,4c!thieno2,3e!1,4-diazepines of general formula (I) wherein R1 represents a hydrogen atom, an alkyl, halogenoalkyl,hydroxyalkyl or dialkylaminoalkyl group, a phenyl group optionally substituted by a methyl, methoxy or nitro group or by a halogen atom, or a pyridyl or pyrimidinyl group or a group of the formula R4- CO- (in which R4 represents a hydrogen atom, a C1 to C17 alkyl group, a C1 or C2 alkoxy group, or a phenyl, tolyl, methoxyphenyl, halogenophenyl, nitrophenyl or pyridyl group); R2 represents a hydrogen, fluorine, chlorine or bromine atom; and R3 represents a chlorine or bromine atom or an alkyl group! and, when R1 is hydrogen, alkyl, halogenoalkyl, hydroxyalkyl or dialkylaminoalkyl, acid addition salts thereof. The novel compounds exhibit pharmacological properties indicating their use as anxiolytics, tranquillizers, sedatives or neuroleptics. Processes for the preparation of the novel compounds and pharmaceutical compositions containing the novel compounds are described and claimed.