发明名称 |
Process for preparing p-chlorophenoxy-acetyl-piperonylpiperazine hydrochloride |
摘要 |
The subject compound, otherwise known as Fipexidum hydrochloride, is obtained by reacting the chloride of p-chlorophenoxyacetic acid with 1,4-bis-piperonylpiperazine, preferably in benzene solution under reflux conditions in the presence of a base such as sodium bicarbonate. The advantages of the process are low cost and high overall conversion due to easy recovery and recycle of relevant substances.
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申请公布号 |
US4225714(A) |
申请公布日期 |
1980.09.30 |
申请号 |
US19790034041 |
申请日期 |
1979.04.27 |
申请人 |
FARMACEUTICI GEYMONAT SUD S.P.A. |
发明人 |
GARDINI, GIAN P.;SCAPINI, GIANCARLO;RAIMONDI, ARMANDO;POIDOMANI, PLACIDO |
分类号 |
C07D317/58;(IPC1-7):C07D405/06 |
主分类号 |
C07D317/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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