| 摘要 |
Title compd. (I; R = H, C1-6 alkyl, haloalkyl, -(CH2)n-X-R5; R5 = H, C1-6 alkenyl, C2-6 alkinyl, C6-10 aryl, C2-8 acyl; X = S, O; n = 0-3; R1 = H, halogen; R2 = halogen, nitro, trifluoromethyl; R4 and R8 are independently H, C1-6 alkyl, C7-10 aralkyl) were prepd. by hydrazine decompn. of phthalyl derivs. (II; M = phthal imide). Thus, 2.3g 5-chloro-2[3-(2-phthalimidoacetamido methyl)-5-methyl-4H-1, 2, 4 -triazol-4-y1 -benzophenone and 0.92g hydrazine hydrate were reacted in 20ml ethanol, and refluxed 1hr to give 5-chloro-2-(3 -glycyl-aminomethyl-5-methyl-4H-1, 2, 4-tetrazol-4-y1)-benzophenone hydrate.
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