| 摘要 |
Compounds of the formula: <IMAGE> in which R<1> and R<2> are independently: hydrogen; alkyl; cycloalkyl, alkenyl; alkynyl; aryl or aralkyl optionally substituted on a phenyl nucleus with one or more halogen atoms or alkyl, alkoxy, hydroxy or trifluoromethyl groups; heteroaryl or heteroaralkyl; or a group having the formula: <IMAGE> in which n is 2 or 3, and R<3> and R<4> are independently C1-4 alkyl or, together with the nitrogen atom to which they are attached, form a heterocycle which may carry a second heteroatom selected from oxygen, sulfur and nitrogen, which nitrogen may carry a C1-4 alkyl radical; or, together with the nitrogen atom to which they are attached, R<1> and R<2> form a heterocycle which may carry a second heteroatom selected from oxygen, sulfur and nitrogen, which nitrogen may carry alkyl or phenyl optionally substituted with one or more halogen atoms or alkyl, alkoxy or trifluoromethyl groups; and their pharmaceutically acceptable acid addition salts have sedative, anticonvulsant and anti-inflammatory activity. |
