24,24-DIFLUORO-25-HYDROXYCHOLECALCIFEROL

摘要

New derivative of vitamin Du,24,24-difluoro-25-hydroxycholecalciferol. The compound is characterized by vitamin D-like activity in its ability to increase intestinal calcium transport, increase serum calcium and inorganic phosphorous concentration and to prevent the development of rickets. It would find ready application as a substitute for vitamin Du and in the treatment of disease states evincing calciumphosphorous imbalance and which are non-responsive to vitamin Du therapy.