发明名称 |
VERFAHREN ZUR HERSTELLUNG VON 4'-SUBSTITUIERTEN 2,4-DICHLOR-ALPHA-(IMIDAZOL-N-YLMETHYL)-DIBENZYLAETHERN |
摘要 |
Novel compounds I and their acid addition salts <IMAGE> in which R is phenyl or phenylthio show activity against some fungi, yeasts and gram positive aerobic and anaerobic bacteria. The new compounds can be prepared by condensing 1-(2',4'- dichlorophenyl)-2-(N-imidazolyl- methyl)-ethanol with 4-chloromethyl- biphenyl, 4-bromomethyl-biphenyl, 1- phenylthio-4-chloromethyl-benzene or 1-phenylthio-4-bromomethyl-benzene in a solvent, most preferably dimethylsulphoxide. |
申请公布号 |
DD143608(A5) |
申请公布日期 |
1980.09.03 |
申请号 |
DD19790212866 |
申请日期 |
1979.05.14 |
申请人 |
RECORDATI SA CHEMICAL AND PHARMACEUTICAL CO,CH |
发明人 |
NARDI,DANTE,IT;MASSARANI,ELENA,IT;TAJANA,ALBERTO,IT;VERONESE,MARIO,IT |
分类号 |
A61K31/415;A61P31/04;C07C29/143;C07D233/60;C07D521/00 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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