STABILIZED AMINOPHYLLINE SOLUTION AND PROCESS THEREFOR

摘要

A stable aqueous aminophylline solution is provided by admixing with said solution disodium edetate as a chelating agent and removing substantially all the carbon dioxide from the solution. In a preferred manner the chelating agent is present in an amount of 0.01 to 1.0% by weight of the solution. Carbon dioxide is preferably removed to optimize aminophylline stability by boiling the solution under an inert gas protection. A stabilized aqueous aminophylline solution results which can be packaged in a container system which would otherwise have a propensity to develop undesired crystal growth in the solution.