| 摘要 |
NEW MATERIAL:A compound shown by the formula I [m is 0 or 1; m is 0-9; R is (OH substituted) lower alkyl or aryl; R<1> is H (when m=1) or acyl having (terminal group substituted) chain hydrocarbon; R<2> is H or lower alkyl, etc. when n=0 and is H when n=1-9; R<3> is H or lower alkyl; R<4> and R<5> are H, OH, etc., R<6> is H or lower alkyl; R<7> is (substituted) alkyl, etc; R<8> and R<9> are H or lower alkyl; D and L are configuration when a carbon atom is asymmetric]. EXAMPLE:6-0-(L-leucyl)-N-acetylmuramyl-aminoisobutyryl-D-isoglutamine methyl ester. USE:Slightly toxic and having strengthened action of immune functions. A drug for preventing infection of the living body and a drug for preventing carcinogenesis. PROCESS:A compound shown by the formula II is esterified, or a compound shown by the formula III is condensed with a compound shown by the formula R<1>-OH. |
