| 摘要 |
<p>Cpds. of formula (I) and their physiologically acceptable acid addn. salts are new. R1 and R2 are each H, halogen, or 1-4C alkyl or alkoxy; X is O, S, CH2, NH or a 2-4C acylimino gp.; p is 2 or 3). 2-(n-amino-isoindolinyl)-imidazoline (Ia) is specifically claimed where R'-R2=H, n=m=1 and p=2. (I) have long lasting antihypertensive activity, e.g. at 10-20mg per day, esp. p.o.</p> |
