发明名称 |
Alkanolamine derivatives |
摘要 |
1-Aryloxy-3-(tri- or tetra-acylamido)-alkylamino-propan-2-ol derivatives, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess beta -adrenergic blocking activity and are useful in the treatment of heart diseases such as angina pectoris, cardiac arrhythmias and hypertension. Representative of the compounds disclosed is 1-(o-chlorophenoxy)-3- beta -(phenylacetamido- gamma -butyramido- gamma -butyramido)-ethylamino-2-propanol.
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申请公布号 |
US4219561(A) |
申请公布日期 |
1980.08.26 |
申请号 |
US19780942815 |
申请日期 |
1978.09.15 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES LTD |
发明人 |
SMITH, LESLIE H |
分类号 |
A61K31/16;A61K31/165;A61K31/18;A61K31/27;A61K31/275;A61K31/335;A61K31/38;A61K31/381;A61K31/395;A61K38/00;A61P25/02;C07C67/00;C07C231/00;C07C231/02;C07C231/10;C07C231/12;C07C233/25;C07C233/36;C07C233/40;C07C233/43;C07C235/06;C07C235/20;C07C237/04;C07C237/06;C07C237/08;C07C237/12;C07C237/22;C07C239/00;C07C253/00;C07C255/54;C07C271/08;C07C273/10;C07C275/10;C07C301/00;C07C303/40;C07C307/06;C07C311/00;C07C313/00;C07C323/20;C07C323/41;C07C323/62;C07C323/67;C07D207/34;C07D233/64;C07D237/08;C07D241/12;C07D277/22;C07D307/38;C07D333/06;(IPC1-7):A61K31/27;A61K31/17 |
主分类号 |
A61K31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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