发明名称 NOVEL DERIVATIVES OF 6-(M-AMINOPHENYL)-2,3,5,6- TETRAHYDROIMIDAZO(2,1-B)THIAZOLES
摘要 <p>The 1- and dl-(racemic) forms of the compounds of the formula ...(I), wherein R is H or CH3, and the non-toxic acid addition salts thereof, useful as anthelmintic compounds are disclosed. The compounds may be prepared by reacting 1- or dl6-(m-aminophenyl)-2,3,5,6-tetrahydroimidazo¢2,1-b!thiazole with an acid of the formula ...(III), wherein R is H or CH3, or with its functional equivalent as an acylating agent, and if desired, when the dl- form of the thiazole starting material is used, resolving the dl- product so as to obtain the 1- form, and if desired, converting an 1- or dl- form of a compound of the Formula (I), into a non-toxic addition salt by reaction with a suitable acid.</p>
申请公布号 CA1084508(A) 申请公布日期 1980.08.26
申请号 CA19770287664 申请日期 1977.09.28
申请人 PFIZER CORPORATION 发明人 LEEMING, MICHAEL R.G.;STUBBS, JOHN K.
分类号 C07D513/04;A61K31/425;A61P33/00;A61P33/10;C07D275/02;C07D275/03;(IPC1-7):07D513/04 主分类号 C07D513/04
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