Aminoalkoxyphenylpyrrolidone antihypertonic agents and use thereof

摘要

Novel aminoalkoxyphenylpyrrolidones of the following formula show antihypertonic activity: wherein R1 is H or OCH3; R2 and R3 are each, independently, H, C1-4 alkyl, OH, C1-6 acyloxy, or C1-3 alkoxy; m and n are each, independently, integers of from 0 to 3; and A is >O, >S >N-R5, or >CH-R5; R5 is H, +TR X is H, C1-4 alkyl, C1-4 alkoxy, halogen, CF3, or OCF3; and Y is O, S or NH; and pharmaceutically acceptable salts thereof.