发明名称 |
ANTIBIOTISCH WIRKSAME BETA -LACTAMVERBINDUNGEN, VERFAHREN ZU DEREN HERSTELLUNG UND SIE ENTHALTENDES ARZNEIMITTEL |
摘要 |
The present invention relates to hitherto unknown compounds of the general formula I: <IMAGE> I in which R1 stands for a phenyl, 4-hydroxyphenyl, 1,4-cyclohexadienyl or a 3-thienyl group; R2 represents a primary amino or a carboxy group; R3 is a hydrogen atom, or a lower alkyl, aryl or aralkyl radical, and A stands for a radical of a beta -lactamase inhibitor containing a beta -lactam ring as well as a carboxy group, A being connected via the carboxy group. The present invention provides new compounds useful in the treatment of bacterial infections. The new compounds are in particular strongly active against beta -lactamase producing bacteria. |
申请公布号 |
DE3005164(A1) |
申请公布日期 |
1980.08.21 |
申请号 |
DE19803005164 |
申请日期 |
1980.02.12 |
申请人 |
LEO PHARMACEUTICAL PRODUCTS LTD.A/S |
发明人 |
OLE,DR.PHIL. GODTFREDSEN,WAGN;VON,DR.RER.NAT. DAEHNE,WELF |
分类号 |
A61K31/43;C07D;C07D498/04;C07D499/00;C07D499/21;C07D499/32;C07D499/42;C07D499/64;C07D499/66;C07D499/68;C07D499/70;C07D499/72;C07D499/74;C07D503/00;C07D519/00 |
主分类号 |
A61K31/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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