| 摘要 |
The product and process of making an in-vivo body implant pharmaceutical carrier of a resorbable ceramic crystalline structure of interconnecting pores capable of the critical controlled time release of pharmaceutical preparations such as proteins, polypeptides, hormones, and other small molecular weight active materials. The ceramic is comprised of aluminum oxide (Al2 O3), calcium oxide (CaO), and phosphorous pentoxide (P2O5) in a controlled weight percent mixture. In the process of making, the mixture is calcined. The calcined mixture is again ground and sieved through screens of two different mesh sizes to obtain desired sizes and mixed with a binder. This mixture is compressed and sintered at a predetermined temperature. The particle sizes of the sieved calcined compound and the sintering temperatures are interrelated to provide a ceramic of a desired pore size for the controlled release of the pharmaceutical.
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