PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS 4-AMINO SUSTITUIDOS DE OLEANDOMICINA,SUS ESTERES II-MONOALCANOILICOS,A MONOALCANOILICOS Y II,2'-DIALCANOILICOS QUE CONTIENEN EN LA POSICION 4UN GRUPO AMINO SUSTITUIDO CON C(0)-C(0)-R3 O-C(ZS)-(C=0)-R

摘要

Derivatives of oleandomycin, its 11-monoalkanoyl, 2-monoalkanoyl and 11,2'-dialkanoyl esters having at the 4''-position an amino group substituted with -C(=O)-C(=O)-R3 or -C(=S)-C(=O)-R3 wherein R3 is alkyl having from one to four carbon atoms, phenyl, substituted phenyl, or a heterocyclyl group, their preparation and use as antibacterial agents is described.