发明名称 ß-LACTAM COMPOUNDS
摘要 The present invention relates to hitherto unknown compounds of the general formula I: <IMAGE> I in which R1 stands for a phenyl, 4-hydroxyphenyl, 1,4-cyclohexadienyl or a 3-thienyl group; R2 represents a primary amino or a carboxy group; R3 is a hydrogen atom, or a lower alkyl, aryl or aralkyl radical, and A stands for a radical of a beta -lactamase inhibitor containing a beta -lactam ring as well as a carboxy group, A being connected via the carboxy group. The present invention provides new compounds useful in the treatment of bacterial infections. The new compounds are in particular strongly active against beta -lactamase producing bacteria.
申请公布号 IE832654(L) 申请公布日期 1980.08.13
申请号 IE19830002654 申请日期 1980.01.21
申请人 LEO PHARMACEUTICAL PRODUCTS LTD.;A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) 发明人
分类号 A61K31/43;C07D;C07D498/04;C07D499/00;C07D499/21;C07D499/32;C07D499/42;C07D499/64;C07D499/66;C07D499/68;C07D499/70;C07D499/72;C07D499/74;C07D503/00;C07D519/00 主分类号 A61K31/43
代理机构 代理人
主权项
地址