| 摘要 |
This invention provides a glaucoma treating composition comprising at least one of carbostyril derivatives represented by the formula <IMAGE> wherein R1 is hydrogen, lower alkyl or lower alkenyl, R2 is hydrogen or a group <IMAGE> wherein R4 is lower alkyl, cycloalkyl, or lower alkyl substituted by phenyl with or without a lower alkoxy substituent on the phenyl nucleus, R3 is a group <IMAGE> wherein R4 is as defined above when R2 is hydrogen, or R3 is hydrogen, hydroxyl, ureido, lower alkynyloxy, lower alkoxy having a lower alkanoyl substitutent, lower alkanoylamino or lower alkenyloxy when R2 is <IMAGE> and the carbon-to-carbon bond between the 3-position and the 4-position of the carbostyril skeleton is a single bond or double bond, and pharmacologically acceptable acid addition salts thereof; and a method of treating glaucoma comprising administering said composition to a patient with glaucoma. |
