PHENYL-TETRAZOLYL-PYRIMIDIN-4-ONE THERAPEUTIC AGENTS

摘要

This specification discloses new therapeutically useful2-(substituted)phenyl-5-(5-1H-tetrazolyl)pyrimidin-4-(3H)-one derivatives which function as inhibitors of allergic reactions; processes for their preparation; pharmaceutical compositions containing them; and methods for treating allergically-mediated diseases in mammals by administration of such derivatives or pharmaceutical compositions thereof. These derivatives may be represented by the structural formula I These compounds and compositions are particularly valuable in the prophylactic treatment of allergic bronchial asthma by oral administration.