| 摘要 |
Title compds. (I, R1, R2, R3 = C1-3 alkyl, C1-3 alkoxy, C1-3 alkylthio, halogen, nitro, cyano, alkoxycarbonyl; M = H, alkali metal, ammonium), useful as an antiphlogistics or an anodyne, were prepd. by heating acetoacetic anilide(II) with formic ester(III) and followed by treating with acetic anhydride to give 2-alkixy-methylene-acetoacetic anilide(IV). The reaction of IV with hydroxyamine in org. solvent gave isoxazole(V), which was reacted with base and followed by reacting with org. strong acid to give I.
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