发明名称 NYA KINAZOLINDERIVAT JEMTE SETT FOR DERAS FRAMSTELLNING OCH FARMACEUTISKA BEREDNINGAR INNEHALLANDE DEM
摘要 Title: "Quinazoline Antihypertensives" Quinazoline antihypertensives of the formula: --- (I) and their pharmaceutically acceptable acid addition salts, wherein R is C1-C4 alXyl, benzyl or (C3-C6 cycloalkyl)methyl, R is C1-C4 alkyl, X is -CH2CH2- substltuted by a phenyl group and optianally by 1 or 2 methyl groups; and R2 is hydrogen, C1-C4 alkyl, or phenyl optionally substituted by 1 or 2 substltuents selected from C1-C4 alkyl, C1-C4 alkoxy, halogen, CF3, -CONR3R4 and -SO2NR3R4 wherein R3 and R4 each represent hydrogen or Cl-C4 alkyl; and processes for preparing the compounds of the formula (I); and pharmaceutical compositions containing them.
申请公布号 SE8000699(L) 申请公布日期 1980.08.01
申请号 SE19800000699 申请日期 1980.01.29
申请人 PFIZER 发明人 CAMPBELL S F;DANILEWICZ J C;GREENGRASS C W
分类号 A61K31/4523;A61K31/505;A61K31/517;A61P9/12;C07D211/46;C07D401/04;(IPC1-7):C07D401/04 主分类号 A61K31/4523
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