发明名称 Process for the preparation of benzopyran derivatives
摘要 The compounds of formula I in which 1) R5 is a hydroxyl group or a hydrogen atom, R7 is a hydrogen atom and R6 and R8, which are identical, are both ethyl groups or both t-butyl groups, or 2) one from R5, R6, R7 and R8 has the formula V in which X is a hydrocarbon chain optionally substituted by an -OH group and containing from 2 to 10 carbon atoms, and the symbols remaining from R5, R6 and R8 are all hydrogen atoms, or one of its pharmaceutically acceptable salts or esters, are prepared by dehydration of a corresponding 2-hydroxy-3-hydro or 2-hydro-3-hydroxy compound. The compounds of formula I are known antiallergic medicaments. The new process makes it possible to obtain them in a purer state and under more certain and more economic conditions than by the prior processes. <IMAGE> <IMAGE>
申请公布号 CH618435(A5) 申请公布日期 1980.07.31
申请号 CH19760014799 申请日期 1976.11.24
申请人 FISONS LTD. 发明人 RICHARD HAZARD
分类号 C07D311/24;(IPC1-7):C07D311/24 主分类号 C07D311/24
代理机构 代理人
主权项
地址