发明名称 |
VERFAHREN ZUR HERSTELLUNG VON GEREINIGTEM S-SULFONIERTEM GAMMA -GLOBULIN |
摘要 |
Process for the production of a highly purified S-sulfonated gammaglobulin by treating an S-sulfonated gammaglobulin obtained by sulfonating a conventional gammaglobulin with an ion exchanger in a buffer solution for development, and thereby absorbing single molecular S-sulfonated gammaglobulin thereto, and eluting the single molecular S-sulfonated gammaglobulin with a buffer solution for elution. This process can give the desired S-sulfonated gammaglobulin having a high content of single molecule and an extremely small anticomplementary activity (e.g. CH50 of 10% or less) and also an excellent shaking stability from the conventional gammaglobulin in an industrial scale. |
申请公布号 |
DE3001187(A1) |
申请公布日期 |
1980.07.31 |
申请号 |
DE19803001187 |
申请日期 |
1980.01.15 |
申请人 |
THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE |
发明人 |
FUNATSU,AKINOBU;OYAMA,SHUZOH;AKIMOTO,YOSHINORI;OHASHI,KOMEI |
分类号 |
A61K39/395;C07K16/06;(IPC1-7):C07G7/00;A61K37/06 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|