摘要 |
5-cyano-1-methylpropyl-2-acetic acid, which is a novel compound as a precursor for the production on industrial scale of 1-methyl-5-aroylpyrol-2-acetic acids having an anti-inflammatory action, is produced by the reaction of 1-methyl-2-(2',2',2',-trihalo-1'-hydroxy ethyl) pyrol with a cyaniding agent. |