发明名称 |
Process for preparing cis-bicyclooctylamines |
摘要 |
A process for preparing antidepresssant 2-phenylbicyclooctylamines of formula (I): <IMAGE> (I) where R1 and R2 represent C1-3 alkyl and Ar represents a phenyl group optionally substituted by up to two halogen atoms, by reduction of a novel enamine intermediate of formula: <IMAGE> (II) where R3 and R4 are hydrogen or taken together represent a single bond and where X is hydrogen, bromine or chlorine.
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申请公布号 |
US4215074(A) |
申请公布日期 |
1980.07.29 |
申请号 |
US19790049672 |
申请日期 |
1979.06.18 |
申请人 |
LILLY INDUSTRIES LTD |
发明人 |
HORWELL, DAVID C;TIMMS, GRAHAM H |
分类号 |
A61K31/135;A61K;A61K31/055;A61K31/13;A61P25/24;A61P25/26;C07C;C07C39/30;C07C67/00;C07C209/00;C07C211/26;C07C211/29;(IPC1-7):C07C83/00 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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