PROCESS FOR THE PREPARATION OF KETOALKYNOIC ACIDS AND USE OF THE PROCESS IN AN IMPROVED SYNTHESIS OF 2- (SUBSTITUTED)-CYCLOPENTANE-1,3,4-TRIONES

摘要

Reaction of a 2-methyl 2-(alkenyl)-1,3-dioxolane with an .alpha.,.omega.-dihalogenoalkane to obtain a 2-methyl-2-(.omega.-chloro-alkynyl)-dioxolane, conversion of the latter to a corresponding nitrile, and hydrolysis of the nitrile to form a ketoalkynoic acid is a novel process for preparing the acid. Use of the process in the synthesis of 2-(substituted)-cyclopentane-1,3,4-triones improves that synthesis.