发明名称 AZABICYLIC COMPOUNDS, METHODS, AND INTERMEDIATES
摘要 <p>Azabicyclic compounds are disclosed having the formula: wherein: A is a member selected from the group consisting of and ; R1 is a member selected from the group consisting of loweralkyl, phenyl, substituted phenyl, phenyl lower alkyl, substituted phenyl lower alkyl, loweralkylamido phenyl, and heterocyclic aryl selected from pyridyl, quinolyl, imidazolyl, pyrazinyl, pyrrolyl, thienyl, thiazolyl, oxazolyl and pyrimidinyl; R3 and R4 are each members selected from the group consisting of hydrogen or loweralkyl; R6 is a member selected from the group consisting of loweralkyl, phenyl, and substituted phenyl; and R7 and R8 are each members selected from the group consisting of hydrogen, halo, loweralkyl, loweralkoxy, and amino. These azabicyclic compounds are useful for their central nervous system depressant and cardiovascular activity.</p>
申请公布号 CA1082188(A) 申请公布日期 1980.07.22
申请号 CA19770270644 申请日期 1977.01.28
申请人 ORTHO PHARMACEUTICAL CORPORATION 发明人 LEVINE, SEYMOUR;KANE, VINAYAK V.
分类号 A61K31/53;A61P9/04;A61P25/20;C07D487/18;(IPC1-7):07D487/18 主分类号 A61K31/53
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