摘要 |
<p>Azabicyclic compounds are disclosed having the formula: wherein: A is a member selected from the group consisting of and ; R1 is a member selected from the group consisting of loweralkyl, phenyl, substituted phenyl, phenyl lower alkyl, substituted phenyl lower alkyl, loweralkylamido phenyl, and heterocyclic aryl selected from pyridyl, quinolyl, imidazolyl, pyrazinyl, pyrrolyl, thienyl, thiazolyl, oxazolyl and pyrimidinyl; R3 and R4 are each members selected from the group consisting of hydrogen or loweralkyl; R6 is a member selected from the group consisting of loweralkyl, phenyl, and substituted phenyl; and R7 and R8 are each members selected from the group consisting of hydrogen, halo, loweralkyl, loweralkoxy, and amino. These azabicyclic compounds are useful for their central nervous system depressant and cardiovascular activity.</p> |