发明名称 |
ZUIVERING VAN GAMMA-GLOBULINE-DERIVAAT. |
摘要 |
Process for the production of a highly purified S-sulfonated gammaglobulin by treating an S-sulfonated gammaglobulin obtained by sulfonating a conventional gammaglobulin with an ion exchanger in a buffer solution for development, and thereby absorbing single molecular S-sulfonated gammaglobulin thereto, and eluting the single molecular S-sulfonated gammaglobulin with a buffer solution for elution. This process can give the desired S-sulfonated gammaglobulin having a high content of single molecule and an extremely small anticomplementary activity (e.g. CH50 of 10% or less) and also an excellent shaking stability from the conventional gammaglobulin in an industrial scale. |
申请公布号 |
NL7909110(A) |
申请公布日期 |
1980.07.21 |
申请号 |
NL19790009110 |
申请日期 |
1979.12.18 |
申请人 |
JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCHINSTITUTE TE KUMAMOTO, JAPAN. |
发明人 |
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分类号 |
A61K39/395;C07K16/06;(IPC1-7):07C103/52;61K39/395;07G7/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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