摘要 |
The compounds of formula I <IMAGE> I wherein R is (a) hydrogen, (b) cycloalkyl of 3 to 7 carbon atoms, (c) alkyl of 2 to 5 carbon atoms monosubstituted by hydroxy, with the proviso that the hydroxyl radical is separated by at least 2 carbon atoms from the carbonylthio moiety to which R is bound, (d) phenyl or phenylalkyl of 7 to 11 carbon atoms, each monosubstituted or independently disubstituted in the phenyl ring by alkyl of 1 to 4 carbon atoms or halogen of atomic number of from 9 to 35, or phenyl or phenylalkyl of 7 to 11 carbon atoms, each monosubstituted or independently disubstituted or independently trisubstituted in the phenyl ring by alkoxy of 1 to 4 carbon atoms, or (e) furyl, benzo[b]furyl, thienyl, benzo[b]thienyl, pyridyl, quinolyl, isoquinolyl, 2- or 3-pyrrolyl or indolyl other than 1-indolyl, R1 and R2 independently are hydrogen or alkyl of 1 to 4 carbon atoms, A is ethylene optionally monosubstituted by hydroxy, or methylene or trimethylene and n is 0, 1 or 2, are useful as antihypertensive agents. |