发明名称 2-Decarboxy-2-hydroxymethyl PGF2 alpha analogs
摘要 This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
申请公布号 US4209645(A) 申请公布日期 1980.06.24
申请号 US19790020599 申请日期 1979.03.15
申请人 UPJOHN CO THE 发明人 NELSON, NORMAN A
分类号 C07C405/00;C07D307/935;C07D319/06;(IPC1-7):C07C177/00 主分类号 C07C405/00
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